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World Bedwetting Day 2016
Bedwetting in childhood: epidemiology, pathophysiology, and treatment
Enuresis, as defined by the International Children's Continence Society, is the occurrence of urinary incontinence during sleep. Bedwetting (i.e. occurs at least twice a week) is a common childhood condition affecting approximately 5–10% of children aged between 5 and 7 years. The prevalence of bedwetting decreases with age, but approximately 1% of bedwetters continue to do so in adulthood. Bedwetting is twice as common in boys as in girls; for example in the UK, the prevalence of bedwetting at least 3 times a week ranges from 5–10% in 9-year-old girls to 15–22% in 7-year-old boys.
The pathophysiology of enuresis is complex and involves the central nervous system (several neurotransmitters and receptors), circadian rhythm (sleep and diuresis), and bladder dysfunction. Most often, enuresis results from a high arousal threshold (i.e. the child does not awaken to void when the bladder is full) combined with either nocturnal polyuria (i.e. over-production of urine at night) or nocturnal detrusor overactivity (and, therefore, reduced bladder capacity), or both...
World Bedwetting Webex
with Professor Serdar Tekgul, Professor Søren Rittig, Dr. Charlotte Van Herzeele, and Professor Johan Vande Walle
Sponsored by Ferring.