You are here

Efficacy of desmopressin and enuresis alarm as first and second line treatment for primary monosymptomatic nocturnal enuresis: prospective randomized crossover study.

By K.W. Kwak, Y.-S. Lee, K.H. Park, and M. Baek.

Journal of Urology, Volume 184, Issue 6, December 2010, Pages 2521-2526

Editor's comments:
Desmopressin and alarm treatment have a similar primary success rate and switching of treatment can be beneficial.This study has focused on the success rate of desmopressin and alarm as a primary treatment or a second line crossover treatment if the first treatment was unsuccessful.  104 children were included in the prospective study.  Following the first line treatment 78% of the desmopressin group and 82% of the alarm treatment had a partial or full response.  Following the second line crossover treatment, 71% of the alarm-desmopressin group and 68% of the desmopressin-alarm group achieved partial or full response [18]. In addition, the authors have found that the relapse rate after desmopressin was higher than after the alarm treatment.  The authors stated that switching to the alternative treatment was beneficial.

Made possible by an
educational grant
from Ferring

E-Alert

 Subscribe to our E-Alert to stay informed of all new content.

Search

The editorial independence of the resource centre is mandatory and recognized by the EAU and Elsevier.
The journal articles, videos and statements published on the resource centre have been selected independently and without influence from Elsevier, European Urology Editors or the sponsor and do not necessarily reflect their opinions or views.

Consensus Guidelines

Practical consensus guidelines for the management of enuresis. 
Evaluation and management of enuresis, a common condition, is not a priority in training programs for medical doctors (MDs), despite being a common condition.