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Copeptin as a novel biomarker in nocturnal enuresis

By B. Nalbantoǧlu, C.M. Yazici, A. Nalbantoǧlu, S. Güzel, B. Topçu, E.Ç. Güzel, M.M. Donma, B. Özdilek, and N.E. Mintaş.

Urology, Volume 82, Issue 5, November 2013, Pages 1120-1123

Editor's comments:
Copeptine, the C-terminal portion of provasopressin, is cosecreted with (arginine) vasopressin, and may be a “novel” biomarker in nocturnal enuresis44 bedwetting and 44 non-bedwetting children were prospectively enrolled in this study.  Plasma levels at 7.00 AM, after at least 12 hours of fasting, were examined for arginine vasopressin (AVP) and copeptine.  The AVP levels in the patient group were not different from the non-bedwetting children, but the copeptine levels were significantly lower in the bedwetting children group.

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Consensus Guidelines

Practical consensus guidelines for the management of enuresis. 
Evaluation and management of enuresis, a common condition, is not a priority in training programs for medical doctors (MDs), despite being a common condition.